Bruxism in Down Syndrome sufferers


Bruxism had been outlined as, a repetitive masticatory muscle exercise characterised by clenching or grinding of the enamel and/or by bracing or thrusting of the mandible and may happen through the day or throughout sleep. The prevalence of bruxism within the common inhabitants has been reported to be between 8% to 31.4% (Manfredini et al., 2013)

The principle intention of this overview was to evaluate the prevalence in bruxism in sufferers with Down Syndrome.


A protocol was registered with the PROSPERO database. Searches had been carried out within the CINHAL, Embase, Medline/PubMed, PsychInfo, Scopus and Internet of Sciences databases. Observational and cross-sectional research reporting on the prevalence of Down Syndrome had been thought of. Two reviewers extracted knowledge independently with research high quality being assessed utilizing the Newcastle-Ottawa Scale (NOS). Meta-analyses had been undertaken utilizing each the fastened and random results fashions.


  • 8 research involving 416 sufferers had been included.
  • 3 research had been carried out in Brazil, 2 in England and one every in Australia, Mexico and the USA.
  • The reported prevalence ranged from 11.4% to 51.8%.
  • Meta-analysis (8 research) discovered a pooled prevalence of bruxism in Down syndrome affected person of : –
    • 33% (95% CI: 22 to 45%) [random-effects model].
    • 35% (95percentCI: 31 to 45%) [fixed-effects model].


The authors concluded: –

This systematic overview and meta-analysis present proof of a major prevalence of bruxism amongst people with DS. The findings spotlight the affiliation of bruxism with different oral well being points and particular chromosomal abnormalities. Complete oral well being assessments, together with diagnostic procedures like Polysomnography, are important for addressing the distinctive oral well being wants of people with DS. Additional research are really helpful with a legitimate instrument for the prognosis.


The authors registered a protocol with the PROSPERO database, though the registration date is proven to be the identical month because the paper was obtained by the journal. A superb vary of databases was searched with 8 small research with pattern sizes of between 22 – 112 being included offering an estimate of the prevalence of bruxism of 33% (95% CI: 22 to 45%) utilizing a random results mannequin. An earlier overview focussing on youngsters and adolescents by Kaddem et al (Dental Elf – 27th Apr 2022) included 9 research associated to down syndrome people 5 of that are included on this present overview producing a a lot bigger estimate for reported clenching and grinding of enamel of 68.2% (95percentCI: 59.8 to 76.6%). The research included on this present overview are primarily cross-sectional and use a variety of diagnostic measures so require caeful interpretation. Future research would profit from a standard framework for evaluation and consequence measures.


Major Paper  

Alam MK, Alsharari AHL, Shayeb MAL, Elfadil S, Cervino G, Minervini G. Prevalence of bruxism in down syndrome sufferers: A scientific overview and meta-analysis. J Oral Rehabil. 2023 Jul 28. doi: 10.1111/joor.13563. Epub forward of print. PMID: 37507203.

Overview protocol in PROSPERO

Different references

Manfredini D, Winocur E, Guarda-Nardini L, Paesani D, Lobbezoo F. Epidemiology of bruxism in adults: a scientific overview of the literature. J Orofac Ache. 2013 Spring;27(2):99-110. doi: 10.11607/jop.921. PMID: 23630682.

Dental Elf – 27th Apr 2022

Tooth grinding in youngsters and adolescents with neurodevelopmental problems




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